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Identification of a novel substrate for TNFα-induced kinase NUAK2

✍ Scribed by Hiroyuki Yamamoto; Seiji Takashima; Yasunori Shintani; Satoru Yamazaki; Osamu Seguchi; Atsushi Nakano; Shuichiro Higo; Hisakazu Kato; Yulin Liao; Yoshihiro Asano; Tetsuo Minamino; Yasushi Matsumura; Hiroshi Takeda; Masafumi Kitakaze


Book ID
116295957
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
408 KB
Volume
365
Category
Article
ISSN
0006-291X

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We have recently determined that -Ile-Tyr- were the two critical residues as a peptide substrate for p60c-src protein tyrosine kinase (Lou, Q. et al., Lett. Peptide Sci., 1995, 2, 289). Here, we report on the design and synthesis of a secondary 'one-bead, one-compound' combinatorial peptide library