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Identification of a Novel Route of Iron Transcytosis across the Mammalian Blood-Brain Barrier

✍ Scribed by IKU MOROO; MAKI UJIIE; BRANDIE L. WALKER; JACQUELINE W.C. TIONG; TIMOTHY Z. VITALIS; DELARA KARKAN; REINHARD GABATHULER; ALEXANDER R. MOISE; WILFRED A. JEFFERIES


Book ID
110058693
Publisher
Informa plc
Year
2003
Tongue
English
Weight
104 KB
Volume
10
Category
Article
ISSN
1073-9688

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✍ Dr. J. B. Fishman; J. B. Rubin; J. V. Handrahan; J. R. Connor; R. E. Fine πŸ“‚ Article πŸ“… 1987 πŸ› John Wiley and Sons 🌐 English βš– 525 KB

The perfusion of rat brain with '251-transferrin resulted in a receptor-mediated uptake of transferrin into the endothelium of the blood-brain barrier followed by its detection in the brain. During a pulsechase experiment, lZSI-transferrin accumulated in the endothelial cells during the pulse, with