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Identification of a novel non-functionalCYP2D6allele,CYP2D6*69, in a Caucasian poor metabolizer individual

✍ Scribed by Andrea Gaedigk; Dorothee Frank; Uwe Fuhr


Publisher
Springer
Year
2008
Tongue
English
Weight
107 KB
Volume
65
Category
Article
ISSN
0031-6970

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## Day Cytochrome P450 2A6 (CYP2A6) is a human enzyme best known for metabolizing tobacco-related compounds, such as nicotine, cotinine (COT), and nitrosamine procarcinogens. CYP2A6 genetic variants have been associated with smoking status, cigarette consumption, and tobacco-related cancers. Our ob