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Identification of a novel IGH-MMSET fusion transcript in a human myeloma cell line with the t(4;14)(p16·3;q32) chromosomal translocation

✍ Scribed by Daniela Intini; Sonia Fabris; Tiziana Storlazzi; Takemi Otsuki; Gabriella Ciceri; Donata Verdelli; Luigia Lombardi; Mariano Rocchi; Antonino Neri

Book ID
108672732
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
217 KB
Volume
126
Category
Article
ISSN
0007-1048

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Establishment of a novel human B-cell li
Establishment of a novel human B-cell line (OZ) with t(14;18)(q32;q21) and aberrant p53 expression was associated with the homozygous deletions of p15INK4B and p16INK4A genes
✍ M. Nagai; M. Fujita; M. Ohmori; S. Matsubara; M. Taniwaki; S. Horiike; T. Tasaka 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 174 KB 👁 1 views

The novel human pre-B cell line OZ was established from a patient with an aggressive form of non-Hodgkin's lymphoma. Karyotypic analysis of both the primary tumour and OZ cells revealed several marker chromosomes, including the t(14;18)(q32;q21) translocation, which involves the Bcl-2 gene, and alte