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Identification of a novel Bcl-2 promoter region that counteracts in a p53-dependent manner the inhibitory P2 region

✍ Scribed by Sebastian Bredow; Daniel E. Juri; Karen Cardon; Yohannes Tesfaigzi

Book ID
116507938
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
468 KB
Volume
404
Category
Article
ISSN
0378-1119

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## Abstract S100B(Ξ²Ξ²) is a dimeric Ca^2+^‐binding protein that is known to inhibit the protein kinase C (PKC)‐dependent phosphorylation of several proteins. To further characterize this inhibition, we synthesized peptides based on the PKC phosphorylation domains of p53 (residues 367‐388), neuromodu