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Identification of a Novel Amplicon at 1q31 in Pancreatic Cancer Cell Lines

✍ Scribed by C.A Tirado; Avery A Sandberg; John F Stone

Book ID
114136916
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
313 KB
Volume
113
Category
Article
ISSN
0165-4608

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## Abstract Several chromosomal regions are recurrently amplified or deleted in lung tumors, but little is known about the underlying genes, which could be important mediators in tumor formation or progression. In lung cancer, the RB1–CCND1–CDKN2A pathway, involved in the G1–S transition, is damage