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Identification of a new ligand for peroxisome proliferator activated receptorα and ã, a lead compound for the therapy of diabetes and obesity

Book ID
117638389
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
114 KB
Volume
13
Category
Article
ISSN
0939-4753

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## Abstract The peroxisome proliferator‐activated receptor‐α (PPAR‐α) plays a key role in lipid metabolism and inflammation. Recently, we demonstrated that administration of the PPAR‐α agonists gemfibrozil and fenofibrate, inhibit the clinical signs of experimental autoimmune encephalomyelitis (EAE