The random amplification of polymorphic DNA (RAPD) using primers of arbitrary nucleotide sequence has been extremely valuable in identifying heritable markers in a variety of systems. The present studies examined whether the RAPD technique can identify large numbers of polymorphisms that can be used
Identification of a new allele ofEs-1segregating in an inbred strain of mice
β Scribed by E. R. Soares
- Publisher
- Springer
- Year
- 1979
- Tongue
- English
- Weight
- 347 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0006-2928
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β¦ Synopsis
A new allele of Es-1, designated Es-1e, has been identified in the mouse. This allele was discovered segregating among the progeny of a strain DBA/2J male and is apparently the result of a spontaneous mutation within this strain. Genetic analyses have shown that this mutation is heritable and, further, that both heterozygous and homozygous progeny are viable and fertile. To date, no discernible deleterious effects have been identified as associated with this mutation.
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