## Abstract Cloned trinitrophenyl (TNP)โspecific cytotoxic T cells (CTL) were obtained from mice transgenic for the ฮฒ chain of the antigenโspecific receptor (TcR) of a K^b^โrestricted, TNPโspecific CTL clone (BT7.4.1). The transgeneโexpressing CTL, specific for TNP/K^b^ were found to select for TcR
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Identification of a major histocompatibility complex class I-restricted T-cell epitope in the tumour-associated antigen, 5T4
โ Scribed by Irina Redchenko; Richard Harrop; Matthew G. Ryan; Robert E. Hawkins; Miles W. Carroll
- Book ID
- 108781849
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 173 KB
- Volume
- 118
- Category
- Article
- ISSN
- 0019-2805
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Experiments were designed in an attempt to identify T-and B-cell epitopes expressed on the 17-kDa early-antigen-restricted (EA-R) polypeptide of the EBV-induced early antigen complex. Using Berzofsky's algorithm, 3 hypothetical T-cell epitopes on p I 7 were synthesized and employed in EBV-specific l