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Identification of a Human cDNA Encoding a Kinase-Defective Cdk5 Isoform

✍ Scribed by Mark Moorthamer; Sabine Zumstein-Mecker; Christine Stephan; Peer Mittl; Bhabatosh Chaudhuri

Book ID
115583020
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
322 KB
Volume
253
Category
Article
ISSN
0006-291X

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Muscle glycogenosis caused by phosphorylase kinase (Phk) deficiency may lead to exercise intolerance, weakness and musculatur atrophy. The gene encoding the muscle isoform of the Phk 7 subunit (7M) is one of the candidate genes in which mutations responsible for this condition should be sought. Here