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Identification of a genetic variant associated with abdominal aortic aneurysms on chromosome 3p12.3 by genome wide association

✍ Scribed by James R. Elmore; Melissa A. Obmann; Helena Kuivaniemi; Gerard Tromp; Glenn S. Gerhard; David P. Franklin; Amy M. Boddy; David J. Carey

Book ID: 119314575
Publisher: Elsevier Science
Year: 2009
Tongue: English
Weight: 483 KB
Volume: 49
Category: Article
ISSN: 1097-6809
DOI: 10.1016/j.jvs.2009.01.041

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## Abstract The genetic analysis of nontumorigenic radiation hybrids generated by transfer of chromosome 3 fragments into the tumorigenic OV‐90 ovarian cancer cell line identified the 3p12.3‐p__cen__ region as a candidate tumor suppressor gene (TSG) locus. In the present study, polymorphic microsat