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Identification of a class of low affinity binding sites for verapamil on liver plasma membranes

✍ Scribed by Berardo Ioannoni; Bernard P. Hughes; Greg J. Barritt

Book ID
115782231
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
394 KB
Volume
42
Category
Article
ISSN
0006-2952

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Binding of somatostatin-14 to rat liver plasma membranes was characterized with 125-labeled[tyr11] somatostatin-14. Binding at 24 degrees C reached a plateau at 50 min and was reversible by synthetic somatostatin-14. Scatchard analysis revealed a single class of binding sites (affinity constant = 2.