✦ LIBER ✦

Identification of a cis-acting regulatory region in the pncB locus of Salmonella typhimurium

✍ Scribed by Kinney, Dennis M. ;Foster, John W.

Publisher: Springer
Year: 1985
Tongue: English
Weight: 624 KB
Volume: 199
Category: Article
ISSN: 0026-8925
DOI: 10.1007/bf00330767

No coin nor oath required. For personal study only.

✦ Synopsis

The pncB locus of the pyridine nucleotide cycle of NAD biosynthesis in Salmonella typhimurium was examined in terms of genetic structure and regulation. The gene appears to be regulated at the level of transcription in response to the end product of the pathway, NAD. Insertions into promotor proximal regions of the gene relinquish it from regulation, while insertions into more distal regions allow retention of regulation. Regulation cannot be restored in trans to strains containing promotor proximal insertions implicating the existence of a cis acting regulatory region.

📜 SIMILAR VOLUMES

Regulation of pyrC expression in Salmone

Regulation of pyrC expression in Salmonella typhimurium: Identification of a regulatory region

✍ Kelln, Rod A. ;Neuhard, Jan 📂 Article 📅 1988 🏛 Springer 🌐 English ⚖ 855 KB

Discontinuity of homology of Escherichia

Discontinuity of homology of Escherichia coli and Salmonella typhimurium DNA in the lac region

✍ Lampel, Keith A. ;Riley, Monica 📂 Article 📅 1982 🏛 Springer 🌐 English ⚖ 591 KB

Partial homology of Salmonella typhimurium DNA to Escherichia coli DNA was demonstrated by Southern hybridization blots to exist on either side of the lac operon of E. coli but no homology was detected between S. typhimurium DNA and about 12 kb of E. coli DNA including the lac genes as well as about

Regulation of NAD metabolism in Salmonel

Regulation of NAD metabolism in Salmonella typhimurium: Genetic analysis and cloning of the nadR repressor locus

✍ Foster, John W. ;Holley-Guthrie, Elizabeth A. ;Warren, Felicity 📂 Article 📅 1987 🏛 Springer 🌐 English ⚖ 834 KB

The nadR locus (99 min) controls the transcription of several genes involved with either the biosynthesis (nadAB) or recycling (pncB) of NAD in Salmonella typhimurium. Point mutations in this locus were found to cause defects either in the transport of nicotinamide mononucleotide (PnuA-), the regula

The involvement of methionine regulatory

The involvement of methionine regulatory mutants in the suppression of B12-dependent homocysteine transmethylase (metH) mutants of Salmonella typhimurium

✍ Whitehouse, Julie M. ;Smith, Derek A. 📂 Article 📅 1974 🏛 Springer 🌐 English ⚖ 614 KB

Identification of a trans-acting regulat

Identification of a trans-acting regulatory factor involved in the control of the pyrimidine pathway in E. coli

✍ Nowlan, Sean F. ;Kantrowitz, Evan R. 📂 Article 📅 1983 🏛 Springer 🌐 English ⚖ 894 KB

A pyrimidine auxotroph of Escherichia coli was isolated which contained a defect in its ability to synthesize both oroate phosphoribosyl transferase, the product of the gene pyrE, and orotidine monophosphate decarboxylase, product of the gene pyrF. A single location on the E. coli linkage map was fo

Integration of minitransposons for expre

Integration of minitransposons for expression of the Escherichia coli elt genes at a preferred site in Salmonella typhimurium identifies a novel putative fimbrial locus

✍ M. Brocchi; M. Giuseppina Covone; Emanuela Palla; C. L. Galeotti 📂 Article 📅 1999 🏛 Springer 🌐 English ⚖ 82 KB