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Identification of a Cell-Specific Transcriptional Enhancer in the First Intron of the Mouse α2(Type I) Collagen Gene

✍ Scribed by Pellegrino Rossi and Benoit De Crombrugghe

Book ID
123634565
Publisher
National Academy of Sciences
Year
1987
Tongue
English
Weight
930 KB
Volume
84
Category
Article
ISSN
0027-8424

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✍ Kenichi Yamane; Hiroyuki Suzuki; Hironobu Ihn; Mitsuyasu Kato; Hirohide Yoshikaw 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 410 KB

## Abstract The α2(I) collagen gene shows cell type‐specific expression, however, the mechanism behind this specificity remains to be determined. We demonstrate here that transforming growth factor‐beta (TGF‐β)‐mediated induction of α2(I) collagen gene is regulated by DNA methylation in a cell type