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Identification of a Cell Division Cycle (cdc2) Homologue in Pneumocystis carinii

✍ Scribed by CHARLES F. THOMAS; MICHAEL GUSTAFSON; ZVEZDANA VUK-PAVLOVIC; EDWARD B. LEOF; ANDREW H. LIMPER

Book ID: 109251396
Publisher: John Wiley and Sons
Year: 1996
Tongue: English
Weight: 141 KB
Volume: 43
Category: Article
ISSN: 1066-5234
DOI: 10.1111/j.1550-7408.1996.tb04952.x

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Specificity is an important aspect of structure-based drug design. Distinguishing between related targets in different organisms is often the key to therapeutic success. Pneumocystis carinii is a fungal opportunist which causes a crippling pneumonia in immunocompromised individuals. We report the id