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Identification of a caspase 3-independent role of pro-apoptotic factor Bak in TNF-α-induced apoptosis

✍ Scribed by Eigo Suyama; Hiroaki Kawasaki; Kazunari Taira

Book ID
117104559
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
475 KB
Volume
528
Category
Article
ISSN
0014-5793

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## Abstract In bone, a large proportion of osteoblasts, the cells responsible for deposition of new bone, normally undergo programmed cell death (apoptosis). Because mechanical loading of bone increases the rate of new bone formation, we hypothesized that mechanical stimulation of osteoblasts might