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Identification of a candidate tumor suppressor gene RHOBTB1 located at a novel allelic loss region 10q21 in head and neck cancer

✍ Scribed by Levent B. Beder; Mehmet Gunduz; Mamoru Ouchida; Esra Gunduz; Akiko Sakai; Kunihiro Fukushima; Hitoshi Nagatsuka; Sachio Ito; Noriyasu Honjo; Kazunori Nishizaki; Kenji Shimizu

Publisher: Springer-Verlag
Year: 2005
Tongue: English
Weight: 364 KB
Volume: 132
Category: Article
ISSN: 1432-1335
DOI: 10.1007/s00432-005-0033-0

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## Communicated by Albert de la Chapelle Allelic deletions, which are suggestive for the presence of tumor suppressor genes, represent a common event in endometrial cancer (EC). Previous loss-of-heterozygosity studies for human chromosome 10q identified a candidate deletion interval at 10q25-q26, w