Identification of 4-(2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-{[(3S)-3-piperidinylmethyl]oxy}-1H-imidazo[4,5-c]pyridin-4-yl)-2-methyl-3-butyn-2-ol (GSK690693), a Novel Inhibitor of AKT Kinase
β Scribed by Rhodes, Nelson; Leber, Jack D.; Clark, Tammy J.; Keenan, Richard M.; Lafrance, Louis V.; Li, Mei; Safonov, Igor G.; Takata, Dennis T.; Venslavsky, Joseph W.; Heerding, Dirk A.
- Book ID
- 111923107
- Publisher
- American Chemical Society
- Year
- 2008
- Tongue
- English
- Weight
- 886 KB
- Volume
- 51
- Category
- Article
- ISSN
- 0022-2623
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## Abstract magnified image Oxidation of metronidazole (**4**) with sodium dichromate yielded the corresponding 2β(2βmethylβ5βnitroβ1__H__βimidazolβ1βyl)acetic acid (**5**) which was esterified with 1βbutanol to give butyl 2β(2βmethylβ5βnitroβ1__H__βimidazolβ1βyl)acetate (**8**). Reaction of the l
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