Identification of 27 putative breast cancer proteomic biomarkers by SELDI-TOF MS
โ Scribed by Bashar Zeidan; N. Murray; R. Cutress; D. Eccles; G. Packham; P. Townsend
- Book ID
- 116443672
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 38 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0748-7983
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## Abstract Surfaceโenhanced laser desorption/ionization timeโofโflight mass spectrometry (SELDIโTOF MS) was used to screen serum samples to identify protein markers for early breast cancer relapse. We collected 67 serum samples from patients with breast cancer (24 preoperative; 23 postoperative wi
## Background Many highโabundant acute phase reactants have been previously detected as potential breast cancer biomarโkers. However, they are unlikely to be specific for breast cancer. Cancerโspecific biomarkers are thought to be among the lower abundant proteins. ## Methods We aimed to detect l