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Identification of 27 5′ CpG islands aberrantly methylated and 13 genes silenced in human pancreatic cancers

✍ Scribed by Hagihara, Atsushi; Miyamoto, Kazuaki; Furuta, Junichi; Hiraoka, Nobuyoshi; Wakazono, Kuniko; Seki, Shuichi; Fukushima, Shoji; Tsao, Ming-Sound; Sugimura, Takashi; Ushijima, Toshikazu


Book ID
110068853
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
214 KB
Volume
23
Category
Article
ISSN
0950-9232

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## Abstract Aberrant methylation of CpG islands (CGI) not only plays a role in gene silencing, but is also a potential cancer biomarker. To identify more CGI aberrantly methylated in human breast cancers, we carried out a genome‐wide search for aberrant methylation, using methylation‐sensitive‐repr