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Identification and use of a neutralizing epitope of parvovirus b19 for the rapid detection of virus infection

✍ Scribed by Ann C. Loughrey; Dr. Hugh J. O'Neill; Peter V. Coyle; Robert Deleys

Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
410 KB
Volume
39
Category
Article
ISSN
0146-6615

No coin nor oath required. For personal study only.

✦ Synopsis

A conserved neutralising epitope was confirmed as the site of specific activity for the monoclonal antibody R92F6. This monoclonal antibody was used to detect B19 viral antigen in serum samples after SDS-PAGE and Western blotting. Twenty samples from the United Kingdom, Ireland, Japan, and the United States were positive with this technique. Serum samples from various control groups were negative.

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