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Identification and regional localization of a human IMPdehydrogenase-like locus (IMPDHL1) at 16p13.13

✍ Scribed by Norman A. Doggett; David F. Callen; Zhong L. Chen; Sarah Moore; Judith G. Tesmer; Lynne A. Duesing; Raymond L. Stallings


Book ID
117592404
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
628 KB
Volume
18
Category
Article
ISSN
0888-7543

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Pseudoxanthoma elasticum (PXE) is an inherited systemic disorder of connective tissue, characterized by progressive calcification of the elastic fibers in the eye, the skin, and the cardiovascular system. The PXE locus has been mapped to chromosome 16p13.1, and was recently further refined to a 500