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Identification and quantification of betulinic acid

✍ Scribed by Tino Galgon; Dirk Höke; Birgit Dräger


Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
65 KB
Volume
10
Category
Article
ISSN
0958-0344

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✦ Synopsis


Betulinic acid was identified in the bark and in the wood of Platanus acerifolia (plane) and of Betula pendula (white birch) by thin layer chromatography, gas chromatography (GC), GC coupled with mass spectrometry (MS), electrospray ionisation MS, and 1 H-nuclear magnetic resonance spectroscopy. Quantitative analysis by GC after derivatisation under mild silylating conditions and using squalane as internal standard showed 3.3% betulinic acid in the cork of plane while the wood content was much lower. The bark of white birch contained 0.3% betulinic acid.


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