Identification and Clinical Application of the Cancer-Specific CpG Promoter Domain DNA Methylation Of CDO1 in Gastric Cancer
โ Scribed by Ema, Akira; Yamashita, Keishi; Ushiku, Hideki; Mieno, Hiroaki; Hosoda, Kei; Moriya, Hiromitsu; Katada, Natsuya; Kikuchi, Shiro; Watanabe, Masahiko
- Book ID
- 127103999
- Publisher
- Elsevier Science
- Year
- 2014
- Tongue
- English
- Weight
- 45 KB
- Volume
- 219
- Category
- Article
- ISSN
- 1072-7515
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## Silencing of p16 INK4a by methylation of the CpG islands in the promoter region has been found to be an alternative mechanism of inactivation in several tumors. However, in gastric carcinoma, the relationship between methylation status and the transcriptional silencing of the p16 gene remains t