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Identification and characterization of variant forms of the gastrin-releasing peptide (GRP)

✍ Scribed by T.J. McDonald; H. Jörnvall; K. Tatemoto; V. Mutt

Book ID
115914672
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
628 KB
Volume
156
Category
Article
ISSN
0014-5793

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Gastrin-releasing peptide (GRP) receptors are present in pancreatic islets, though their regulation is unknown except for homologous desensitization. The modulation of binding of GRP to mouse pancreatic islets and INS-1 cells was studied. At 60 min (steady-state), total binding of [ 125 I-Tyr 15 ] G