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Identification and characterization of two dermorphins from skin extracts of the Amazonian frog Phyllomedusa bicolor

✍ Scribed by Giuseppina Mignogna; Cinzia Severini; Maurizio Simmaco; Lucia Negri; Giuliana Falconieri Erspamer; Günther Kreil; Donatella Barra


Book ID
115926118
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
478 KB
Volume
302
Category
Article
ISSN
0014-5793

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In this study, two novel antimicrobial peptides from the skin secretions of the marsh frog, __Rana ridibunda__, named temporin‐Ra and temporin‐Rb, were identified and purified using RP‐HPLC. Temporin‐Ra and temporin‐Rb are composed of 14 and 12 amino acids, respectively. Our results show that these