Identification and characterization of the mouse MutS homolog 5:Msh5
β Scribed by Chengtao Her; Xiling Wu; Wei Wan; Norman A. Doggett
- Publisher
- Springer-Verlag
- Year
- 1999
- Tongue
- English
- Weight
- 574 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0938-8990
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The mutator mutation mut5-1 has been characterized with respect to a range of parameters which have been used to describe DNA repair mutants of yeast. No marked effect of the mutation on UV-mutability at lower doses was apparent. Diploids homozygous for the mutation are deficient in UV-induced recom
## Abstract Postreplicative mismatch repair (MMR) corrects polymerase errors arising during DNA replication. Consistent with this role, the __Saccharomyces cerevisiae MMR__ genes __MSH2, MSH6,__ and __PMS1__ were reported to be transcriptionally upregulated during late G~1~ phase of the cell cycle.