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Identification and Characterization of the Human SCAN Domain Zinc-Finger GeneZNF449

✍ Scribed by Kuntian Luo; Jie Li; Yanhui Cui; Meng Xu; Jian Yuan; Wenwen Tang; Bo Wan; Long Yu

Book ID
106469451
Publisher
Springer
Year
2006
Tongue
English
Weight
576 KB
Volume
33
Category
Article
ISSN
0301-4851

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Identification and characterization of SKAT-2, a novel Th2-specific zinc finger gene
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We have identified a novel Kruppel-type zinc finger (ZF) gene, SKAT-2, which is selectively expressed by murine Th2 cells. The protein encoded by this gene has 14 C2H2-type ZF tandemly arrayed at its C terminus and N-terminal SCAN box and KRAB domains. SKAT-2 is tissue restricted in expression at th