The purpose of this study was to characterize mefenamic acid (MA) from commercial samples and samples crystallized from different solvents. Various techniques used for characterization included microscopy (hot stage microscopy, scanning electron microscopy), intrinsic dissolution rate, differential
Identification and characterization of solid-state nature of 2-chloromandelic acid
β Scribed by Quan He; Jesse Zhu; Hassan Gomaa; Michael Jennings; Sohrab Rohani
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 316 KB
- Volume
- 98
- Category
- Article
- ISSN
- 0022-3549
No coin nor oath required. For personal study only.
β¦ Synopsis
The racemate and enantiomers of 2-chloromandelic acid were characterized by SS-NMR, XRPD, and FTIR. The binary melting point phase diagram was constructed by DSC (differential scanning calorimetry). The solid-state nature of 2-chloromandelic acid was identified to be a racemic compound. The crystal structure of racemic compound was determined to be monoclinic P2 1 /c.
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