Expression of hepatitis C virus NS5B pro
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Koji Ishii; Yoshinobu Tanaka; Chan-Choo Yap; Hideki Aizaki; Yoshiharu Matsuura;
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Article
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1999
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John Wiley and Sons
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English
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The nonstructural protein 5B (NS5B) of hepatitis C virus (HCV) is considered to possess RNA-dependent RNA polymerase (RdRp) activity and to play an essential role for the viral replication. In this study, we expressed the NS5B protein of 65 kd by a recombinant baculovirus. With the highly purified N