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Identification and characterization of RNA-dependent RNA polymerase activity in recombinant Japanese encephalitis virus NS5 protein

โœ Scribed by F. Yu; F. Hasebe; S. Inoue; E. G. M. Mathenge; K. Morita


Publisher
Springer Vienna
Year
2007
Tongue
English
Weight
344 KB
Volume
152
Category
Article
ISSN
1432-8798

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Expression of hepatitis C virus NS5B pro
โœ Koji Ishii; Yoshinobu Tanaka; Chan-Choo Yap; Hideki Aizaki; Yoshiharu Matsuura; ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 271 KB

The nonstructural protein 5B (NS5B) of hepatitis C virus (HCV) is considered to possess RNA-dependent RNA polymerase (RdRp) activity and to play an essential role for the viral replication. In this study, we expressed the NS5B protein of 65 kd by a recombinant baculovirus. With the highly purified N