Identification and Characterization of Reactive Metabolites in Natural Products-Driven Drug Discovery

Identification and characterization of a

Identification and characterization of a principal oxidation impurity in clopidogrel drug substance and drug product

✍ Arivozhi Mohan; M. Hariharan; E. Vikraman; G. Subbaiah; B.R. Venkataraman; D. Sa 📂 Article 📅 2008 🏛 Elsevier Science 🌐 English ⚖ 628 KB

Natural products and drug discovery. Can

Natural products and drug discovery. Can thousands of years of ancient medical knowledge lead us to new and powerful drug combinations in the fight against cancer and dementia?

✍ Ji, Hong-Fang; Li, Xue-Juan; Zhang, Hong-Yu 📂 Article 📅 2009 🏛 Nature Publishing Group 🌐 English ⚖ 653 KB

Evaluation of liquid chromatography coup

Evaluation of liquid chromatography coupled with high-field 1H NMR spectroscopy for drug metabolite detection and characterization: The identification of paracetamol metabolites in urine and bile

✍ M. Spraul; M. Hofmann; J. C. Lindon; R. D. Farrant; M. J. Seddon; J. K. Nicholso 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 814 KB

[Progress in Drug Research] Natural Comp

[Progress in Drug Research] Natural Compounds as Drugs Volume I Volume 65 || Strain improvement for production of pharmaceuticals and other microbial metabolites by fermentation

✍ Petersen, Frank; Amstutz, René 📂 Article 📅 2008 🏛 Birkhäuser Basel ⚖ 202 KB

Isolation of circulating metabolites in

Isolation of circulating metabolites in drug discovery using high-performance liquid chromatography, and their identification by liquid chromatography coupled with tandem mass spectrometry and nuclear magnetic resonance spectroscopy

✍ Hong Kim; Wenqing Feng; Tze-Ming Chan; Diane Rindgen; Matthew Bryant; Kathleen A 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 221 KB 👁 3 views

Isolation of circulating metabolites in drug discovery using high-performance liquid chromatography, and their identification by liquid chromatography coupled with tandem mass spectrometry and nuclear magnetic resonance spectroscopy One of the major components of modern drug discovery is the structu

LC-MS–MS in MRM Mode for Detection and S

LC-MS–MS in MRM Mode for Detection and Structural Identification of Synthetic Hypoglycemic Drugs Added Illegally to ‘Natural’ Anti-Diabetic Herbal Products

✍ Wensheng Pang; Huiwan Yang; Zhisheng Wu; Meixia Huang; Juan Hu 📂 Article 📅 2009 🏛 Springer 🌐 English ⚖ 410 KB