Identification and Characterization of Novel Genes Located at the t(1;15)(p36.2;q24) Translocation Breakpoint in the Neuroblastoma Cell Line NGP

Analysis of mutations and identification

Analysis of mutations and identification of several polymorphisms in the putative promoter region of the P34CDC2-related CDC2L1 gene located at 1P36 in melanoma cell lines and melanoma families

✍ Yongmei Feng; Jiaqi Shi; Alisa M. Goldstein; Margaret A. Tucker; Mark A. Nelson 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 French ⚖ 257 KB

## Abstract Chromosome 1 abnormalities are the most commonly detected aberrations in many cancers including malignant melanoma. Partial deletions and an allelic loss of the chromosome 1p36 region observed in melanoma indicate the presence of putative tumor suppressor gene(s) in this region. A candi