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Identification and characterization of C1orf36, a transcript highly expressed in photoreceptor cells, and mutation analysis in retinitis pigmentosa

✍ Scribed by Giovanni Lavorgna; Marta Lestingi; Carmela Ziviello; Francesco Testa; Francesca Simonelli; Maria Pia Manitto; Rosario Brancato; Maurizio Ferrari; Ernesto Rinaldi; Alfredo Ciccodicola; Sandro Banfi


Book ID
117054417
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
469 KB
Volume
308
Category
Article
ISSN
0006-291X

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Transgenic mice expressing a dominant mutation in the gene for the phototransduction molecule rhodopsin undergo retinal degeneration similar to that experienced by patients with the retinal degenerative disease, retinitis pigmentosa (RP). Although the mutation is thought to cause photoreceptor degen