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Identification and characterization of a novel murine beta-defensin-related gene

✍ Scribed by Gillian M. Morrison; Mark Rolfe; Fiona M. Kilanowski; Sally H. Cross; Julia R. Dorin

Publisher
Springer-Verlag
Year
2002
Tongue
English
Weight
233 KB
Volume
13
Category
Article
ISSN
0938-8990

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The 32-residue peptide, RK-1, a novel kidney-derived three disulfide-bonded member of the antimicrobial h-defensin family, was synthesized by the continuous flow Fmoc-solid phase method. The crude, cleaved and S-reduced linear peptide was both efficiently folded and oxidized in an acidic solution of