𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Identical mutation in 55% of the ATM alleles in 11 Norwegian AT families: evidence for a founder effect

✍ Scribed by Laake, Kirsten; Telatar, Milhan; Geitvik, Gry A; Hansen, Rita Øien; Heiberg, Arvid; Andresen, Anne Marie; Gatti, Richard; Børresen-Dale, Anne-Lise


Book ID
110024691
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
484 KB
Volume
6
Category
Article
ISSN
1018-4813

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Detailed haplotype analysis at the TP53
✍ Sonia Garritano; Federica Gemignani; Edenir Inez Palmero; Magali Olivier; Ghysla 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 345 KB

Due to patterns of migration, selection, and population expansion, founder effects are common among humans. In Southern Brazil, a recurrent TP53 mutation, p.R337H, is detected in families with cancer predisposition. We have used whole locus resequencing and high-density single nucleotide polymorphis