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ICOS-gene variants are not associated with atopic disease susceptibility in European children

✍ Scribed by Katja C. Beier; Steffi Humberdros; Heiko Witt; Sabina Illi; Franz Rüschendorf; Renate Nickel; Young-Ae Lee; Susanne Lau; Ulrich Wahn; Eckard Hamelmann


Book ID
110895263
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
78 KB
Volume
20
Category
Article
ISSN
0905-6157

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Filaggrin loss-of-function variants are
✍ J. Van Limbergen; R.K. Russell; E.R. Nimmo; Y. Zhao; H. Liao; H.E. Drummond; G. 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 100 KB

Background: Pediatric inflammatory bowel disease (IBD) has a high prevalence of coexistent atopy. Filaggrin (FLG) loss-of-function variants (null-alleles) are associated with eczema and asthma in association with eczema. The aim was to assess the contribution of FLG null-alleles to pediatric IBD sus