Induction of apoptosis by tamoxifen and
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Paul A. Ellis; Gloria Saccani-Jotti; Robert Clarke; Stephen R.D. Johnston; Eliza
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Article
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1997
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John Wiley and Sons
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French
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Hormonal breast cancer therapies have traditionally been considered cytostatic, but recent pre-clinical data suggest that anti-oestrogens can induce apoptosis. The aim of this study was to assess whether tamoxifen (TAM) and ICI 182780 (ICI) could induce apoptosis in human breast cancer, and whether