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IC-P1-008: Comparison of amyloid plaque contrast generated by T2-, T2*, and susceptibility-weighted magnetic resonance imaging methods in transgenic mice

✍ Scribed by Ryan Chamberlain; Denise Reyes; Geoffrey L. Curran; Malgorzata Marjanska; Thomas M. Wengenack; Joseph F. Poduslo; Michael Garwood; Clifford R. Jack


Book ID
118463583
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
220 KB
Volume
4
Category
Article
ISSN
1552-5260

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## Abstract One of the hallmark pathologies of Alzheimer's disease (AD) is amyloid plaque deposition. Plaques appear hypointense on __T__~2~‐weighted and __T__‐weighted MR images probably due to the presence of endogenous iron, but no quantitative comparison of various imaging techniques has been r