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IBX in aqueous medium: a green protocol for the Biginelli reaction

✍ Scribed by Takale, Santosh; Parab, Sanket; Phatangare, Kiran; Pisal, Rajaram; Chaskar, Atul


Book ID
117995743
Publisher
The Royal Society of Chemistry
Year
2011
Tongue
English
Weight
737 KB
Volume
1
Category
Article
ISSN
2044-4753

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## Abstract Biginelli three‐component condensation of an aldehyde, β‐keto ester, and urea proceeds smoothly on the surface of the silver salt of heteropolyacid (HPA), i.e. Ag~3~PW~12~O~40~, in water to afford the corresponding 3,4‐dihydropyrimidinones in high‐to‐quantitative yields under mild condi