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Ibuprofen-Cyclodextrin Inclusion Complex Formation using Supercritical Carbon Dioxide

✍ Scribed by YUICHI TOZUKA; TAKAYUKI FUJITO; KUNIKAZU MORIBE; KEIJI YAMAMOTO


Publisher
Springer Netherlands
Year
2006
Tongue
English
Weight
268 KB
Volume
56
Category
Article
ISSN
0923-0750

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Phase-solubility techniques were used to assess the formation of inclusion complex between itraconazole and beta-cyclodextrin. The stability constant and free energies of transfer of itraconazole from aqueous solution to the cavity of beta-cyclodextrin were calculated. Itraconazole solubility in sup