Phase solubility and inclusion complex o
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Ali H. Al-Marzouqi; Ibrahim Shehatta; Baboucarr Jobe; Ali Dowaidar
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Article
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2006
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John Wiley and Sons
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English
β 375 KB
Phase-solubility techniques were used to assess the formation of inclusion complex between itraconazole and beta-cyclodextrin. The stability constant and free energies of transfer of itraconazole from aqueous solution to the cavity of beta-cyclodextrin were calculated. Itraconazole solubility in sup