𝔖 Bobbio Scriptorium
✦   LIBER   ✦

IBD: A vascular disorder? the case for heparin therapy

✍ Scribed by Dr. Joshua R. Korzenik

Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
864 KB
Volume
3
Category
Article
ISSN
1078-0998

No coin nor oath required. For personal study only.

✦ Synopsis

In recent years, heparin has emerged as a possible therapy for inflammatory bowel disease (IBD). Several recent, strongly positive, open-labeled series of heparin in both ulcerative colitis (UC) and Crohn's disease (CD) reinforce the work of Gaffney and co-workers that suggested a benefit of heparin in UC. Although counterintuitive as a therapy for a disorder characterized by bleeding, heparin is intriguing also for implications with regard to the pathophysiology of UC and CD. Although the thromboembolic complications and hypercoagulable state associating flares of both UC and CD suggest that heparin may produce a benefit by treating microthrombi in the intestinal

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