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Iap2 is required for a sustained response in the Drosophila Imd pathway

✍ Scribed by Susanna Valanne; Anni Kleino; Henna Myllymäki; Jussi Vuoristo; Mika Rämet

Book ID: 116401605
Publisher: Elsevier Science
Year: 2007
Tongue: English
Weight: 773 KB
Volume: 31
Category: Article
ISSN: 0145-305X
DOI: 10.1016/j.dci.2007.01.004

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## Abstract Summary: The __Sil__ gene encodes a cytosolic protein required for mouse embryonic midline and left/right axial development. Based on the phenotype of __Sil__ mutant embryos, we hypothesized that Sil may be required for the activity of Sonic Hedgehog (Shh), a secreted signaling molecule