IA-2 Antibodies Are Only Positive in Association With GAD 65 and Islet Cell Antibodies in Islet Transplanted Insulin-Dependent Diabetes Mellitus Patients
โ Scribed by C Jaeger; M.D Brendel; B.J Hering; M Eckhard; K Federlin; R.G Bretzel
- Book ID
- 117235799
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 137 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0041-1345
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๐ SIMILAR VOLUMES
Blood was drawn from 74 children, 3-16 years old, at diagnosis of Type 1 (insulin-dependent) diabetes and before the first insulin injection. Insulin autoantibodies were detected with a polyethylen-glycol-method in 27/74 (36.4%) and with an immuno-electrophoretic method in 6/74 (8.1%). Islet cell cy
Islet cell antibodies and glutamic acid decarboxylase II (GAD II) antibodies have been discussed in the autoimmune pathogenesis of insulin-dependent diabetes mellitus (IDDM). Hence, immunosuppressants, intravenous immunoglobulins, and plasmapheresis have been used in an effort to modulate autoimmune