I2 Rearrangement reaction: Synthesis of isofregenedane type diterpenoids
✍ Scribed by Julio G. Urones; Asunción Jorge; Isidro S. Marcos; Pilar Basabe; David Díez; Narciso M. Garrido; Anna M. Lithgow; M. Olimpia C.F. da Fonseca; Jesús M.L. Rodilla
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- French
- Weight
- 149 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0040-4039
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A new stereoselective approach to polyoxygenated atisane-type diterpenes starting from (S)-(+)-carvone is described. The key steps involve an intramolecular Diels-Alder reaction, an unusual intramolecular diazo ketone cyclopropanation of an unsaturated ketone, and a regioselective endocyclic cleava
A new diastereoselective approach to oxygenated spongiane diterpenes starting from (R)-(-)-carvone is described. The carvone is incorporated as the B ring in the final spongiane framework using a BABABCABCD approach, which involves an intramolecular Diels-Alder reaction and the regioselective ring-o