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I171V germline mutation in theNBS1gene significantly increases risk of breast cancer

✍ Scribed by Krzysztof Rożnowski; Danuta Januszkiewicz-Lewandowska; Maria Mosor; Monika Pernak; Maria Litwiniuk; Jerzy Nowak


Book ID
106377623
Publisher
Springer US
Year
2007
Tongue
English
Weight
213 KB
Volume
110
Category
Article
ISSN
0167-6806

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Germline mutations 657del5 of the NBS1 g
✍ Jan Steffen; Dorota Nowakowska; Anna Niwińska; Dorota Czapczak; Anna Kluska; Mag 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 French ⚖ 85 KB

## Abstract Recent studies have demonstrated that heterozygous carriers of the __NBS1__ 657del5 mutation have an increased risk for familial and bilateral breast cancer, but similar studies in consecutive breast cancer patients were inconclusive. Here, in a study of 562 nonselected breast cancer pa