I. A unique deaminated metabolite of sulfamethazine [4-amino-N-(4, 6-dimethyl-2-pyrimidinyl) benezenesulfonamide] in swine

Effect of high dietary nitrate on the di

Effect of high dietary nitrate on the disposition of sulfamethazine [4-amino-N-(4,6-dimethyl-2-pyrimidinyl)benzenesulfonamide] in swine

✍ Paulson, Gaylord D.; Aschbacher, Peter W. 📂 Article 📅 1990 🏛 American Chemical Society 🌐 English ⚖ 393 KB

A Doubly Interpenetrated Layer Structure

A Doubly Interpenetrated Layer Structure in the 1:1 Cocrystal Formed Between Pyromellitic Acid and 4-Amino-N-(4,6-dimethyl-2-pyrimidinyl)benzenesulfonamide

✍ Hadi D. Arman, Edward R. T. Tiekink 📂 Article 📅 2013 🏛 Springer 🌐 English ⚖ 425 KB

Reaction of 1,3-dimethyl-5-nitro-6-chlor

Reaction of 1,3-dimethyl-5-nitro-6-chlorouracil with derivatives of 5-amino-4-mercaptopyrimidine and 3-amino-2-mercaptopyridine

✍ M. P. Nemeryuk; N. I. Traven'; N. A. Nersesyan; T. S. Safonova 📂 Article 📅 1985 🏛 Springer US 🌐 English ⚖ 66 KB

Discovery of 5-[[4-[(2,3-Dimethyl-2 H -i

Discovery of 5-[[4-[(2,3-Dimethyl-2 H -indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-benzenesulfonamide (Pazopanib), a Novel and Potent Vascular Endothelial Growth Factor Receptor Inhibitor †

✍ Harris, Philip A.; Boloor, Amogh; Cheung, Mui; Kumar, Rakesh; Crosby, Renae M.; 📂 Article 📅 2008 🏛 American Chemical Society 🌐 English ⚖ 591 KB

Discovery of 5-[[4-[(2,3-Dimethyl-2 H -i

Discovery of 5-[[4-[(2,3-Dimethyl-2 H -indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-benzenesulfonamide (Pazopanib), a Novel and Potent Vascular Endothelial Growth Factor Receptor Inhibitor †

✍ Harris, Philip A.; Boloor, Amogh; Cheung, Mui; Kumar, Rakesh; Crosby, Renae M.; 📂 Article 📅 2008 🏛 American Chemical Society 🌐 English ⚖ 591 KB

Inhibition of the vascular endothelial growth factor (VEGF) signaling pathway has emerged as one of the most promising new approaches for cancer therapy. We describe herein the key steps starting from an initial screening hit leading to the discovery of pazopanib, N 4 -(2,3-dimethyl-2H-indazol-6-yl)

Copper(II) Complexes with 4-Amino- N -[4

Copper(II) Complexes with 4-Amino- N -[4,6-dimethyl-2-pyrimidinyl]benzenesulfonamide. Synthesis, Crystal Structure, Magnetic Properties, EPR, and Theoretical Studies of a Novel Mixed μ-Carboxylato, NCN-Bridged Dinuclear Copper Compound

✍ Gutiérrez, L.; Alzuet, G.; Borrás, J.; Castiñeiras, A.; Rodríguez-Fortea, A.; Ru 📂 Article 📅 2001 🏛 American Chemical Society 🌐 English ⚖ 153 KB