Hysteresis in the glucose permeability versus pH characteristic for a responsive hydrogel membrane

✍ Scribed by John P. Baker; Ronald A. Siegel

• Publisher: John Wiley and Sons
• Year: 1996
• Tongue: English
• Weight: 408 KB
• Volume: 17
• Category: Article
• ISSN: 1022-1336
• DOI: 10.1002/marc.1996.030170607

✦ Synopsis

Abstract

A side‐by‐side diffusion cell was used to study the permeability of glucose through a temperature‐ and pH‐sensitive poly(N‐isopropylacrylamide‐co‐methacrylic acid) hydrogel membrane. At fixed temperature (37°C), lowering pH in one side of the cell induced hydrogel volume collapse and strongly attenuated glucose permeation across the membrane. Hysteresis was observed in the glucose permeability versus pH characteristic.