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Hypoxic enhancement of exosome release by breast cancer cells

✍ Scribed by Hamish W King, Michael Z Michael, Jonathan M Gleadle

Book ID
119897465
Publisher
BioMed Central
Year
2012
Tongue
English
Weight
293 KB
Volume
12
Category
Article
ISSN
1471-2407

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Exposure of cultured human breast cancer cells (MCF-7) to medroxyprogesterone acetate (MPA) prior to treatment with adriamycin (ADR) enhanced the effect of the cytotoxic drug on cell yield after further growth of viable cells. Pretreatment with oestradiol (E2) produced similar synergism, but no such