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Hypoxic and normoxic in vitro cultures maintain similar numbers of long-term reconstituting hematopoietic stem cells from mouse bone marrow

✍ Scribed by Yanjuan Tang; Camilla Halvarsson; Pernilla Eliasson; Jan-Ingvar Jönsson

Book ID: 118441158
Publisher: Elsevier Science
Year: 2012
Tongue: English
Weight: 207 KB
Volume: 40
Category: Article
ISSN: 0301-472X
DOI: 10.1016/j.exphem.2012.07.005

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✍ Phillips, R. A. 📂 Article 📅 1980 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 431 KB

## Abstract Mature, functional lymphocytes rapidly disappear from long‐term cultures of mouse bone marrow cells and never reappear. One reason for the loss of B lymphocytes is that the optimal culture conditions for maintenance of myeloid stem cells are suboptimal for lymphocyte survival. However,