𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Hypoxia stimulates breast carcinoma cell invasion through MT1-MMP and MMP-2 activation

✍ Scribed by Muñoz-Nájar, U M; Neurath, K M; Vumbaca, F; Claffey, K P

Book ID
110070297
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
544 KB
Volume
25
Category
Article
ISSN
0950-9232

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Expression of MMP-2 and MMP-9, their inh
Expression of MMP-2 and MMP-9, their inhibitors, and the activator MT1-MMP in primary breast carcinomas
✍ Jones, J. Louise; Glynn, P.; Walker, Rosemary A. 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 321 KB 👁 2 views

Enhanced expression of the type IV collagenases MMP-2 and MMP-9, or lack of their inhibitors TIMP-1 and TIMP-2, has been associated with tumour invasion and metastatic potential in several experimental models. Regulation of enzyme activity is clearly a key step in tumour invasion, and recently a pot

Imatinib inhibits colorectal cancer cell
Imatinib inhibits colorectal cancer cell growth and suppresses stromal-induced growth stimulation, MT1-MMP expression and pro-MMP2 activation
✍ Xanthi N. Stahtea; Andeas E. Roussidis; Ioannis Kanakis; George N. Tzanakakis; G 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 French ⚖ 243 KB

## Abstract Tumor progress depends on the proliferation of cancer cells, their interactions with stroma and the proteolytic action of enzymes. Colon cancer is c‐kit positive and responsive to the specific tyrosine kinase inhibitor imatinib. We investigated the effect of imatinib on the proliferatio